pd-1/pd-l1 has become a research hotspot in tumor immunotherapy in recent years. tumor cells recruit immunosuppressive cells and cytokines by overexpressing pd-1/pd-l1, reduce the antigenicity of tumor cells, and tilt the balance of immune microenvironment from steady state to immunosuppression. this process is called immune editing.
immune editing includes three processes: clearing, balancing, and escaping. tumor cells ultimately evade the anti-tumor effects of the body's immune system through immune editing, forming clinically detectable tumors.
in recent years, research related to pd-1 antibodies has emerged, which may become a major anti-tumor tool.
background of pd1 antibody (bxc-be0146):
the invivomab anti mouse pd-1 (cd279):
research fields: cancer biology, immune checkpoint proteins, immunology;
clone number: rmp1-14;
antigen: pd-1;
host source: rats;
antibody subtype: igg2a, κ;
molecular weight: 150 kda;
recommended homotypic control: invivomab anti mouse pd-1 (cd279) product number: be0089;
concentration: usually between 4 and 11 mg/ml depending on the batch;
recommended dilution buffer: invivopure ph 7.0 dilution buffer, product number: ip0070;
艾美捷pd1抗体(bxc-be0146)背景:
该invivomab 抗小鼠 pd-1 (cd279)(invivomab anti-mouse pd-1 (cd279)):
研究领域:癌症生物学, 免疫检查点蛋白, 免疫学;
克隆号:rmp1-14;
抗原:pd-1;
宿主来源:大鼠;
抗体亚型:igg2a, κ;
分子量:150 kda;
推荐同型对照:invivomab 抗小鼠 pd-1 (cd279)货号为:be0089;
浓度:因批次可能不同,通常在4-11 mg/ml之间;
推荐的稀释缓冲液:invivopure ph 7.0 稀释缓冲液,货号:ip0070;
pd1抗体(bxc-be0146)相关研究:
体内单克隆抗体抗小鼠pd-1 (cd279) (克隆j43)
体内单克隆抗体抗人类pd-1 (cd279) (克隆j116)
体内单克隆抗体抗人类pd-1 (cd279) (克隆j110)
体内单克隆抗体抗小鼠pd-1 (cd279) (克隆29f.1a12™)
体内加上抗小鼠pd-1(cd279)(克隆j43)
体内加上抗小鼠pd-1(cd279)(克隆29f.1a12™)
recombimab 抗小鼠 pd-1 (cd279) (d265a) (克隆 rmp1-14-cp151)
recombimab抗小鼠pd-1 (cd279) (克隆rmp1-14-cp157)
recombimab抗小鼠pd-1 (cd279) (克隆rmp1-14-cp162)
体内sim抗人类pd-1(纳武利尤单抗生物类似药)
体内加上抗小鼠pd-1(cd279)(克隆29f.1a12™)
体内sim抗人pd-1(帕博利珠单抗生物类似药)(克隆帕博利珠单抗)
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