中英文说明丨艾美捷Aniracetam阿尼西坦
description
aniracetam is a nootropic ampakine that exhibits anxiolytic and neuroprotective activities. aniracetam acts as a positive allosteric modulator of ampa receptors, slowing receptor deactivation; it also acts on d2 receptors, 5-ht2a receptors, and nicotinic acetylcholine receptors (nachrs), likely displaying agonist activity. aniracetam decreases anxiety in vivo in the condition fear stress test, elevated plus maze test, and in social interaction tests. additionally, this compound inhibits h2o2-induced deficits in long-term potentiation and neuron viability. aniracetam shows some clinical benefit in the enhancement of cognitive deficits associated with stroke and alzheimer’s disease.
product info
cas no.72432-10-1
purity≥98%
formulac12h13no3
formula wt.219.24
chemical name1-(4-methoxybenzoyl)-2-pyrrolidinone
iupac name1-(4-methoxybenzoyl)pyrrolidin-2-one
synonymro-13-5057, draganon, sarpul
melting point121-122°c
solubilitysoluble in chloroform and ethyl acetate. slightly soluble in ethanol. insoluble in water.
appearancewhite or almost white crystalline powder
艾美捷aniracetam#lkt-a5326-25mg是一种促智安帕因，表现出抗焦虑和神经保护活性.阿尼西坦作为ampa受体的正变构调节剂，减缓受体失活;它还作用于d2受体、5-ht2a受体和烟碱乙酰胆碱受体 （nachrs），可能显示激动剂活性。aniracetam在恐惧压力测试，升高加迷宫测试和社会互动测试中减少体内焦虑。此外，该化合物抑制h2o2诱导的长期增强和神经元活力缺陷.阿尼西坦在增强与中风和阿尔茨海默病相关的认知缺陷方面显示出一些临床益处。
aniracetam参数说明：
cas#：72432-10-1
纯度：≥98%
公式：c12h13no3
配方重量：219.24
化学名称：1-（4-甲氧基苯甲酰基）-2-吡咯烷酮
iupac名称：1-（4-甲氧基苯甲酰基）吡咯烷-2-酮
同义词：ro-13-5057， 德拉加农， 萨普尔
熔点：121-122°c
溶解度：溶于氯仿和乙酸乙酯。微溶于乙醇。不溶于水。
外观：白色或几乎白色结晶粉末
aniracetam文献参考：
wang yf, li cc, cai jx. aniracetam attenuates h2o2-induced deficiency of neuron viability, mitochondria potential and hippocampal long-term potentiation of mice in vitro. neurosci bull. 2006 sep;22(5):274-80. pmid: 17690727.
jin r, clark s, weeks am, et al. mechanism of positive allosteric modulators acting on ampa receptors. j neurosci. 2005 sep 28;25(39):9027-36. pmid: 16192394.
nakamura k. aniracetam: its novel therapeutic potential in cerebral dysfunctional disorders based on recent pharmacological discoveries. cns drug rev. 2002 spring;8(1):70-89. pmid: 12070527.
nakamura k, kurasawa m. anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism. eur j pharmacol. 2001 may 18;420(1):33-43. pmid: 11412837.
ito i, tanabe s, kohda a, et al. allosteric potentiation of quisqualate receptors by a nootropic drug aniracetam. j physiol. 1990 may;424:533-43. pmid: 1975272.
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aniracetam is a nootropic ampakine that exhibits anxiolytic and neuroprotective activities. aniracetam acts as a positive allosteric modulator of ampa receptors, slowing receptor deactivation; it also acts on d2 receptors, 5-ht2a receptors, and nicotinic acetylcholine receptors (nachrs), likely displaying agonist activity. aniracetam decreases anxiety in vivo in the condition fear stress test, elevated plus maze test, and in social interaction tests. additionally, this compound inhibits h2o2-induced deficits in long-term potentiation and neuron viability. aniracetam shows some clinical benefit in the enhancement of cognitive deficits associated with stroke and alzheimer’s disease.
product info
cas no.72432-10-1
purity≥98%
formulac12h13no3
formula wt.219.24
chemical name1-(4-methoxybenzoyl)-2-pyrrolidinone
iupac name1-(4-methoxybenzoyl)pyrrolidin-2-one
synonymro-13-5057, draganon, sarpul
melting point121-122°c
solubilitysoluble in chloroform and ethyl acetate. slightly soluble in ethanol. insoluble in water.
appearancewhite or almost white crystalline powder
艾美捷aniracetam#lkt-a5326-25mg是一种促智安帕因，表现出抗焦虑和神经保护活性.阿尼西坦作为ampa受体的正变构调节剂，减缓受体失活;它还作用于d2受体、5-ht2a受体和烟碱乙酰胆碱受体 （nachrs），可能显示激动剂活性。aniracetam在恐惧压力测试，升高加迷宫测试和社会互动测试中减少体内焦虑。此外，该化合物抑制h2o2诱导的长期增强和神经元活力缺陷.阿尼西坦在增强与中风和阿尔茨海默病相关的认知缺陷方面显示出一些临床益处。
aniracetam参数说明：
cas#：72432-10-1
纯度：≥98%
公式：c12h13no3
配方重量：219.24
化学名称：1-（4-甲氧基苯甲酰基）-2-吡咯烷酮
iupac名称：1-（4-甲氧基苯甲酰基）吡咯烷-2-酮
同义词：ro-13-5057， 德拉加农， 萨普尔
熔点：121-122°c
溶解度：溶于氯仿和乙酸乙酯。微溶于乙醇。不溶于水。
外观：白色或几乎白色结晶粉末
aniracetam文献参考：
wang yf, li cc, cai jx. aniracetam attenuates h2o2-induced deficiency of neuron viability, mitochondria potential and hippocampal long-term potentiation of mice in vitro. neurosci bull. 2006 sep;22(5):274-80. pmid: 17690727.
jin r, clark s, weeks am, et al. mechanism of positive allosteric modulators acting on ampa receptors. j neurosci. 2005 sep 28;25(39):9027-36. pmid: 16192394.
nakamura k. aniracetam: its novel therapeutic potential in cerebral dysfunctional disorders based on recent pharmacological discoveries. cns drug rev. 2002 spring;8(1):70-89. pmid: 12070527.
nakamura k, kurasawa m. anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism. eur j pharmacol. 2001 may 18;420(1):33-43. pmid: 11412837.
ito i, tanabe s, kohda a, et al. allosteric potentiation of quisqualate receptors by a nootropic drug aniracetam. j physiol. 1990 may;424:533-43. pmid: 1975272.
制药领域pH自动加液系统控制酸碱
GB/T24807 GB/T24808 电梯电磁兼容方案配置!GB/T24807 GB/T24808
电缆、水管弯曲试验机 技术指标
豪森维尔玻璃棉生产厂家
茶叶铝膜袋装25克背封自动包装机设备
中英文说明丨艾美捷Aniracetam阿尼西坦
城市供暖用聚氨酯发泡保温管厂家供应
保养实验电炉的具体方法
【干货】DR平板探测器两大主要类型
日本smc电磁阀内部结构图
养护室控制仪安装及使用方法
快速卷帘门开启方式、安装及用途分类
SY-2型混凝土压力泌水仪-压力泌水仪
新品推荐——A30粮库全自动三维激光扫描仪
水下桥梁检测方案-铁路水下桩基础检测潜水员
简述弯管机弯曲管材变形、管材材质与弯管机数据关系
供暖烟囱新建
管式反应器满足不同工作环境的工艺需要
简析步进电机主要特点和特性
氧指数测定仪由燃烧筒、试样夹、流量控制系统及点火器组成