BE0101体内单克隆抗小鼠PD-L1(B7-H1)说明书
product details
the 10f.9g2 monoclonal antibody reacts with mouse pd-l1 (programmed death ligand 1) also known as b7-h1 or cd274. pd-l1 is a 40 kda type i transmembrane protein that belongs to the b7 family of the ig superfamily. pd-l1 is expressed on t lymphocytes, b lymphocytes, nk cells, dendritic cells, as well as ifnγ stimulated monocytes, epithelial cells and endothelial cells. pd-l1 binds to its receptor, pd-1, found on cd4 and cd8 thymocytes as well as activated t and b lymphocytes and myeloid cells. engagement of pd-l1 with pd-1 leads to inhibition of tcr-mediated t cell proliferation and cytokine production. pd-l1 is thought to play an important role in tumor immune evasion. induced pd-l1 expression is common in many tumors and results in increased resistance of tumor cells to cd8 t cell mediated lysis. in mouse models of melanoma, tumor growth can be transiently arrested via treatment with antibodies which block the interaction between pd-l1 and pd-1. the 10f.9g2 antibody has been shown to block the interaction between pd-l1 and pd-1 and between pd-l1 and b7-1 (cd80).
bioxcell艾美捷be0101体内单克隆抗小鼠pd-l1(b7-h1)抗体:
10f.9g2单克隆抗体与小鼠pd-l1（程序性死亡配体1）反应，也称为b7-h1或cd274。pd-l1是一种40 kda的i型跨膜蛋白，属于ig超家族的b7家族。pd-l1在t淋巴细胞，b淋巴细胞，nk细胞，树突状细胞以及ifnγ刺激的单核细胞，上皮细胞和内皮细胞上表达。pd-l1与其受体pd-1结合，pd-4存在于cd8和cd1胸腺细胞以及活化的t和b淋巴细胞和骨髓细胞上。
bioxcell艾美捷体内单克隆抗小鼠pd-l1(b7-h1)抗体规格：
# bxc-be0101
isotyperat igg2b, κ
recommended isotype control(s)invivomab rat igg2b isotype control, anti-keyhole limpet hemocyanin
recommended dilution bufferinvivopure ph 6.5 dilution buffer
immunogenmouse cd274
reported applicationsin vivo pd-l1 blockade
immunofluorescence
immunohistochemistry (frozen)
flow cytometry
western blot
formulationpbs, ph 6.5
contains no stabilizers or preservatives
endotoxin<2eu/mg (<0.002eu/μg)
determined by lal gel clotting assay
purity>95%
determined by sds-page
sterility0.2 μm filtered
productionpurified from tissue culture supernatant in an animal free facility
purificationprotein g
rridab_10949073
molecular weight150 kda
storagethe antibody solution should be stored at the stock concentration at 4°c. do not freeze.
同种型大鼠igg2b， κ
推荐的同种型对照体内mab大鼠igg2b同种型对照，抗锁孔帽贝血蓝蛋白
推荐的稀释缓冲液体内纯ph 6.5 稀释缓冲液
免疫原鼠标cd274
报告的应用程序体内pd-l1阻断
免疫荧光
免疫组化（冷冻）
流式细胞术
蛋白质印迹
配方pbs，ph 6.5
不含稳定剂或防腐剂
内毒素<2eu/mg （<0.002eu/μg）
通过lal凝胶凝血测定法测定
纯度>95%
由sds-page 决定
无菌0.2 μm 过滤
生产从无动物设施中的组织培养上清液中纯化
纯化蛋白g
里德ab_10949073
分子量150 千达
存储抗体溶液应以4°c的储备浓度储存。 不要冻结。
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the 10f.9g2 monoclonal antibody reacts with mouse pd-l1 (programmed death ligand 1) also known as b7-h1 or cd274. pd-l1 is a 40 kda type i transmembrane protein that belongs to the b7 family of the ig superfamily. pd-l1 is expressed on t lymphocytes, b lymphocytes, nk cells, dendritic cells, as well as ifnγ stimulated monocytes, epithelial cells and endothelial cells. pd-l1 binds to its receptor, pd-1, found on cd4 and cd8 thymocytes as well as activated t and b lymphocytes and myeloid cells. engagement of pd-l1 with pd-1 leads to inhibition of tcr-mediated t cell proliferation and cytokine production. pd-l1 is thought to play an important role in tumor immune evasion. induced pd-l1 expression is common in many tumors and results in increased resistance of tumor cells to cd8 t cell mediated lysis. in mouse models of melanoma, tumor growth can be transiently arrested via treatment with antibodies which block the interaction between pd-l1 and pd-1. the 10f.9g2 antibody has been shown to block the interaction between pd-l1 and pd-1 and between pd-l1 and b7-1 (cd80).
bioxcell艾美捷be0101体内单克隆抗小鼠pd-l1(b7-h1)抗体:
10f.9g2单克隆抗体与小鼠pd-l1（程序性死亡配体1）反应，也称为b7-h1或cd274。pd-l1是一种40 kda的i型跨膜蛋白，属于ig超家族的b7家族。pd-l1在t淋巴细胞，b淋巴细胞，nk细胞，树突状细胞以及ifnγ刺激的单核细胞，上皮细胞和内皮细胞上表达。pd-l1与其受体pd-1结合，pd-4存在于cd8和cd1胸腺细胞以及活化的t和b淋巴细胞和骨髓细胞上。
bioxcell艾美捷体内单克隆抗小鼠pd-l1(b7-h1)抗体规格：
# bxc-be0101
isotyperat igg2b, κ
recommended isotype control(s)invivomab rat igg2b isotype control, anti-keyhole limpet hemocyanin
recommended dilution bufferinvivopure ph 6.5 dilution buffer
immunogenmouse cd274
reported applicationsin vivo pd-l1 blockade
immunofluorescence
immunohistochemistry (frozen)
flow cytometry
western blot
formulationpbs, ph 6.5
contains no stabilizers or preservatives
endotoxin<2eu/mg (<0.002eu/μg)
determined by lal gel clotting assay
purity>95%
determined by sds-page
sterility0.2 μm filtered
productionpurified from tissue culture supernatant in an animal free facility
purificationprotein g
rridab_10949073
molecular weight150 kda
storagethe antibody solution should be stored at the stock concentration at 4°c. do not freeze.
同种型大鼠igg2b， κ
推荐的同种型对照体内mab大鼠igg2b同种型对照，抗锁孔帽贝血蓝蛋白
推荐的稀释缓冲液体内纯ph 6.5 稀释缓冲液
免疫原鼠标cd274
报告的应用程序体内pd-l1阻断
免疫荧光
免疫组化（冷冻）
流式细胞术
蛋白质印迹
配方pbs，ph 6.5
不含稳定剂或防腐剂
内毒素<2eu/mg （<0.002eu/μg）
通过lal凝胶凝血测定法测定
纯度>95%
由sds-page 决定
无菌0.2 μm 过滤
生产从无动物设施中的组织培养上清液中纯化
纯化蛋白g
里德ab_10949073
分子量150 千达
存储抗体溶液应以4°c的储备浓度储存。 不要冻结。
美国LEESON eco Ag电机特征及优点
鞋帮和衬里耐折测试用皮革耐折牢度试验机试验方法
避雷器放电计数器校验仪应用及技术特点
德国EPK MINITEST 405 超声波壁厚测厚仪
二氧化氯发生器技术要求
BE0101体内单克隆抗小鼠PD-L1(B7-H1)说明书
TFP104-000型德国HYDAC温度传感器在安装和使用时应注意事项
建筑隔墙板吊挂历装置技术特点
如何提高污泥烘干机的工作效率
信百诺告诉您如何购买液压试验机更划算
地埋式污水处理设备特点及适应范围
600L高粘度行星搅拌机的主要工作步骤
商洛市冷铆钳可铆接Φ12 Φ14 Φ16 Φ18的铆钉
<询>云南矿山布袋除尘器哪家好？工业布袋除尘器耀先厂家13年品牌服务
未来高铁什么样？真空管道＋高温超导助力磁浮列车“奔跑”
活塞车床用的操作系统和加工范围
圆形水浴氮吹仪厂家来教你如何使用圆形水浴氮吹仪
变压器直阻速测仪的技术特点
河北瑞奥告诉您， 99%的人不了解工业机器人的构造
国产安全柜的分型以及八个操作规程